![]() Here, we report longitudinal electrophysiological assessments conducted during the trial. We reported a Phase 1 study of autologous purified Schwann cell suspension transplantation into the injury epicenter of participants with complete subacute thoracic SCI, observing no clinical improvements. Neurophysiologic data may provide otherwise imperceptible circuit information that has rarely been acquired in biologics clinical trials in SCI. The clinical examination may be insufficiently sensitive and specific to reveal evolving changes in neural circuits after severe injury. Neurophysiological testing can provide quantitative information about motor, sensory, and autonomic system connectivity following spinal cord injury (SCI). 3Miller School of Medicine, The Interdisciplinary Stem Cell Institute, The University of Miami, Miami, FL, United States. ![]() 2The Department of Neurological Surgery, Miller School of Medicine, The University of Miami, Miami, FL, United States.1The Miami Project to Cure Paralysis, Miller School of Medicine, The University of Miami, Miami, FL, United States. ![]()
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